A clinical study on patients with fatty liver disease reveals how the alkaloid acts on VEGF and blood pressure There’s a plant that researchers struggle to fit into a single category. It acts on blood sugar, on fats, on inflammation, and now it seems to be talking to blood vessels too. It’s called berberine, an…
Crataegus monogyna: polyphenols, cardiovascular health and new nutraceutical prospects Crataegus monogyna, hawthorn, is a plant rich in polyphenols, flavonoids and phenolic acids with documented effects on the cardiovascular system, lipid metabolism and oxidative stress. A scientific deep dive for nutraceutical formulators. There is a category of plants that folk phytotherapy has used for centuries in…
How the compounds of Origanum majorana act on hormones, oxidative stress, and ovarian fertility Preclinical study on Origanum majorana in a PCOS model induced by dehydroepiandrosterone (DHEA). Serum metabolomics analysis identifies apigenin and oleic acid as main compounds. Computational mapping of molecular interactions reveals key targets in the aromatase enzyme and estrogen receptor. Oxidative stress…
Saffron Crocetin and Coronary Artery Disease: What a Controlled Study Reveals A randomized controlled trial evaluated the effect of crocetin, a saffron carotenoid, on inflammation, oxidative stress and leptin in patients with coronary artery disease. A scientific look at the mechanisms, study design and implications for cardiovascular nutraceutical research. Saffron’s deep red colour conceals a…
A randomized controlled trial examines the effects of Ganoderma lucidum spore oil (GLSO) on cholesterol, LDL, HDL, and liver health Ganoderma lucidum spore oil (GLSO) was evaluated in a randomized controlled trial involving 113 participants with borderline-high triglycerides. The extract reduced triglycerides, total cholesterol and LDL, increased HDL, and improved liver markers without affecting kidney…
An Italian trial on 225 patients shows the contribution of Serenoa repens and Cucurbita pepo to minoxidil and finasteride An Italian multicenter randomized trial on 225 subjects with androgenetic alopecia evaluated a supplement for androgenetic alopecia based on Serenoa repens, Cucurbita pepo, L-cystine and vitamin C, added to therapy with minoxidil and finasteride, measuring its…
Phytochemistry meets neuroscience: what the literature says about Asparagus racemosus, oxidative stress and memory Asparagus racemosus, known as Shatavari, shows preclinical evidence of antioxidant, anti-inflammatory, and anticholinesterase properties of interest for neuroprotection in Alzheimer’s disease, although clinical data are still limited. Asparagus racemosus, known in Ayurveda as Shatavari, is a plant from the traditional Indian…
Probiotics, omega-3, vitamins and minerals in pediatrics: what the science says after thirteen clinical trials analyzed Analysis of the Frontiers in Pediatrics 2026 systematic review on oral supplements for chronic diseases in children: probiotics, omega-3, vitamins, minerals. Efficacy, safety, contract manufacturing insights for the pediatric nutraceutical sector. A chronic diagnosis in a child changes the…
A meta-analysis on 2,570 patients documents significant effects on osteocalcin, BAP and TRAP
2026 meta-analysis on melatonin and bone mineral density (BMD) in menopausal women. 10 RCTs, 497 participants. Positive signal at the femoral neck with 3 mg doses. Inconclusive evidence on sleep, menopausal symptoms, mood, sexual function, BMI and insulin. There is a hormone that is almost always discussed in relation to sleep, and almost never in…