A clinical study on patients with fatty liver disease reveals how the alkaloid acts on VEGF and blood pressure There’s a plant that researchers struggle to fit into a single category. It acts on blood sugar, on fats, on inflammation, and now it seems to be talking to blood vessels too. It’s called berberine, an…
Crataegus monogyna: polyphenols, cardiovascular health and new nutraceutical prospects Crataegus monogyna, hawthorn, is a plant rich in polyphenols, flavonoids and phenolic acids with documented effects on the cardiovascular system, lipid metabolism and oxidative stress. A scientific deep dive for nutraceutical formulators. There is a category of plants that folk phytotherapy has used for centuries in…
How the compounds of Origanum majorana act on hormones, oxidative stress, and ovarian fertility Preclinical study on Origanum majorana in a PCOS model induced by dehydroepiandrosterone (DHEA). Serum metabolomics analysis identifies apigenin and oleic acid as main compounds. Computational mapping of molecular interactions reveals key targets in the aromatase enzyme and estrogen receptor. Oxidative stress…
Monacolins from fermented red rice could be banned in food supplements in the European Union. On 13 May 2026, the SCoPAAF approved a European Commission proposal aimed at banning their use. This is a significant update for manufacturers, distributors and companies in the nutraceutical sector. However, the ban is not yet definitively in force: the…
Saffron Crocetin and Coronary Artery Disease: What a Controlled Study Reveals A randomized controlled trial evaluated the effect of crocetin, a saffron carotenoid, on inflammation, oxidative stress and leptin in patients with coronary artery disease. A scientific look at the mechanisms, study design and implications for cardiovascular nutraceutical research. Saffron’s deep red colour conceals a…
The disclosure obligations on unsold products introduce new requirements for European businesses under the Ecodesign for Sustainable Products Regulation (ESPR). The provisions establish how the economic operators concerned must report information on unsold consumer products they have discarded, with the aim of increasing transparency and helping to prevent the destruction of goods. The new provisions…
A randomized controlled trial examines the effects of Ganoderma lucidum spore oil (GLSO) on cholesterol, LDL, HDL, and liver health Ganoderma lucidum spore oil (GLSO) was evaluated in a randomized controlled trial involving 113 participants with borderline-high triglycerides. The extract reduced triglycerides, total cholesterol and LDL, increased HDL, and improved liver markers without affecting kidney…
Mivagyn vaginal tablets clinical study on vaginal pH and flora Vaginal wellbeing depends on a delicate balance between bacterial flora, mucosal hydration, and pH. A lactobacilli-dominated flora contributes to lactic acid production and helps maintain an acidic vaginal environment that is unfavorable to the proliferation of opportunistic microorganisms. When this balance is altered, symptoms such…
An Italian trial on 225 patients shows the contribution of Serenoa repens and Cucurbita pepo to minoxidil and finasteride An Italian multicenter randomized trial on 225 subjects with androgenetic alopecia evaluated a supplement for androgenetic alopecia based on Serenoa repens, Cucurbita pepo, L-cystine and vitamin C, added to therapy with minoxidil and finasteride, measuring its…
Revaginal Vaginal Douche for Intimate Wellness Revaginal vaginal douche is a medical device formulated with hyaluronic acid and lactic acid to promote vaginal mucosal hydration, help maintain physiological vaginal pH, and support intimate comfort. In a clinical study involving 20 women, the mean 16-item VSQ score decreased from 5.05 to 2.89 after 3 weeks of…