Harnessing the Power of Ayurvedic Medicinal Plants for Asthma Management: Exploring Phytochemical Mechanisms
Asthma, a chronic inflammatory condition of the bronchi often allergy-induced, leads to difficulty breathing and wheezing. Traditional herbal remedies, deeply rooted in various cultures, have been explored as a potential base for future anti-asthmatic preparations.
Conventional asthma therapies face challenges like side effects and high costs, impacting treatment compliance and individuals’ quality of life. A recent narrative review article delved into the protective phytochemical substances of select Ayurvedic herbs, studying their actions on immune responses and signaling cascades in inflammatory asthma models.
The study extensively reviewed literature from 2006 to 2022 across various international databases like PubMed, PubChem Compound, Wiley Online Library, Science Direct, Springer Link, and Google Scholar.
Highlighting the mechanisms of action of phytochemical substances found in traditional medicinal plants, this research illustrates how these compounds alleviate pulmonary disturbances in both in vivo and in vitro asthma models. It delineates the phytochemical mechanisms of select Ayurvedic botanical preparations used in asthma treatment.
Active phytochemicals such as curcumin, withaferin-A, piperine, glabridin, glycyrrhizin, 18 β-glycyrrhetinic acid, trans-cinnamaldehyde, α-terpineol, thymoquinone, eugenol, shogaol, and gingerol could potentially intervene in asthma by controlling inflammation and modulating the immune system, according to the researchers.
This study presents the state-of-the-art research on Ayurvedic herbs’ phytochemistry that demonstrate preventive or therapeutic activities against asthma. It highlights the potential development of strategies to create personalized, low-cost, and minimally side-effect-inducing herbal therapeutics.
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