Effects of anthocyanin-rich supplementation on cognition in cognitively healthy middle-aged and older adults
The prevalence of age-related cognitive decline is increasing as the world’s population ages, putting the independence and quality of life of the elderly at risk. Anthocyanin, as a subclass of dietary flavonoids, may have a beneficial impact on cognitive outcomes.
The objective of this study was to examine the effects of dietary anthocyanin supplementation on cognition in cognitively healthy middle-aged and elderly adults.
PubMed, ScienceDirect, CINAHL, EMBASE, ProQuest, and Cochrane databases were consulted and thirteen studies were included in this meta-analysis. Anthocyanin supplementation significantly improved the processing speed of older adults (95%CI 0.08, 0.44; P = 0.004). However, no significant differences were observed between the intervention and control groups in memory, attention, executive function, and psychomotor performance.
Current neuroimaging studies have found promising effects of anthocyanin supplementation on brain activation and cerebral perfusion.
In conclusion, anthocyanin supplementation may preserve cognitive processing speed and neuroactivities in the elderly, improving their daily functioning and quality of life. This review provides useful insights to guide the direction and methodological designs of future studies aimed at exploring the mechanisms underlying anthocyanins.
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Source: Feng RC, Dong YH, Hong XL, Su Y, Wu XV. Effects of anthocyanin-rich supplementation on cognition of the cognitively healthy middle-aged and older adults: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2023 Feb 10;81(3):287-303.
