Introduction to Alzheimer’s disease and current therapies Alzheimer’s disease (AD) is the most common form of neurodegenerative dementia and represents a growing health challenge. In 2022, about 55 million people were affected, and it is estimated that the number could reach 139 million by 2050. Current treatments are only symptomatic and show limited efficacy: they…
A Natural Aid Against Cognitive Decline Mild cognitive impairment (MCI) is a condition characterized by a decline in cognitive functions, such as memory, language, and attention, that does not significantly impair daily activities. It is considered an intermediate stage between normal cognitive aging and more severe conditions such as dementia and Alzheimer’s disease. This early…
Herbal-Based Products in the Treatment of Subjective Cognitive Decline in the Elderly: A Literature Review Subjective cognitive decline (SCD) is a self-perceived worsening of cognitive functioning, particularly in the memory domain, which cannot be verified by neuropsychological tests. SCD lies on a continuum of healthy cognitive aging and is conceptualized as the preclinical phase of…
Effects of Melissa officinalis extract containing rosmarinic acid on cognition in older adults without dementia Previous in vitro and in vivo studies in Alzheimer’s disease (AD) models have reported that rosmarinic acid (RA) can inhibit the formation of amyloid-β fibrils as well as the oligomerization and deposition of amyloid-β protein. Melissa officinalis (M. officinalis) extract…