Oral solution to prevent respiratory infections in children
Recurrent respiratory infections (RRIs) are one of the leading causes of illness in children, especially those under 10 years of age. In addition to compromising a child’s well-being, they cause numerous days of absence from school and work. In this context, Revilan, a dietary supplement based on resveratrol, β-glucan, zinc, and vitamins, has shown remarkable clinical efficacy in reducing infectious episodes in children with RRIs.
Revilan Clinical Study: Efficacy Against Respiratory Infections
Gruppo FarmaImpresa conducted a multicenter observational clinical study on 270 children with an average age of 5.7 years and a diagnosis of recurrent respiratory infections. Patients were treated with Revilan at a dose of 10 mL/day for 3 months, and the results were compared to the period before taking the supplement.
Measured indicators:
- Number of total acute respiratory infections (ARI)
- Lower respiratory tract infections (LRTI)
- Acute otitis media (AOM)
- Pharyngotonsillitis and rhinopharyngitis
- Episodes of loss of appetite
- Days of fever
- School and work absences
- Antibiotic treatments
Significant Results Across All Clinical Parameters
Treatment with Revilan led to a statistically significant reduction (p<0.001) in the frequency of all observed infections.
Among the most significant results:
- Acute Respiratory Infections: from 1.07 to 0.17 episodes/patient/month (84% reduction)
- Acute Respiratory Tract Infections: from 0.52 to 0.09 (−83%)
- Otitis media: from 0.33 to 0.04 (−88%)
- Average days of fever: from 1.18 to 0.19 (-83%)
- School absences: from 1.96 to 0.39 days/month
- Parental work absences: from 1.44 to 0.26 days/month
- Antibiotic treatments: significantly reduced (-89%)
Visual Data: Reduction in Infections, School, and Work Absences
As part of the Revilan clinical study, the results were also graphically represented to highlight the treatment’s impact on three key parameters:
The first graph shows a sharp decrease in the average number of acute respiratory infection episodes, which dropped from over 3 episodes per child before treatment to about 0.5 episodes during the 3 months of Revilan administration (p<0.001). This result confirms the product’s effectiveness in significantly strengthening immune defenses and preventing infections.
The second graph also reports on the socioeconomic benefits. Children’s school absences decreased from almost 6 days per month to less than 1 day, showing a significant reduction (p<0.001). Parental work absences also dropped from about 4 days monthly to just over 1, thereby improving family productivity and reducing the indirect costs of childhood illnesses.
These data confirm that Revilan not only reduces the frequency of infections but also improves the quality of life for families and the efficiency of the school and work systems.
Mechanism of Action: Immunomodulatory Synergy
The combination of resveratrol, β-glucan, zinc, and vitamins B and D was designed to act on multiple fronts:
- Resveratrol: antioxidant, anti-inflammatory, and antiviral action
- β-Glucan: stimulates innate and adaptive immunity
- Zinc: supports the immune system and reduces viral replication
- Vitamins D, B6, and B12: regulate the immune response and reduce oxidative stress
The synergy between these components led to a potentiated effect compared to the use of individual molecules, as also confirmed by previous studies.
Reduced Antibiotic Use and Indirect Costs
Another interesting finding from the study was the significant reduction in the use of antibiotics. This leads to fewer side effects, a lower risk of antibiotic resistance, and economic savings for the healthcare system and families. Furthermore, the decrease in school and work absences helps to reduce the overall socioeconomic impact of childhood infections.
Conclusion
The Revilan clinical study confirms that supplementation with resveratrol, β-glucan, zinc, and vitamins is both effective and safe in reducing the frequency and intensity of respiratory infections in children. The product showed benefits across all analyzed parameters, also improving the quality of life for the young patients and their families. Revilan is positioned as a preventive solution for pediatric immune support.
Are you looking for a clinically validated nutraceutical solution? We are manufacturers of dietary supplements, dermo-cosmetics, and medical devices. Revilan is available for your company as a finished product or in private label.
