The influence of turmeric and curcumin on female reproductive processes
Turmeric (Curcuma longa L.) is a spice with a millennia-old tradition in Ayurvedic medicine and is also widely used in industrialized countries.
Its health properties have been described by numerous preclinical, clinical, and review studies.
To date, however, only one publication has examined its action on reproductive processes, focusing specifically on carcinogenesis and not on turmeric’s action on a healthy reproductive system.
This recent publication is the first attempt to compile and synthesize available information on the activity of turmeric and its components, curcumin in particular, on a healthy female reproductive system, as well as data on their ability to prevent and treat certain reproductive disorders and dysfunctions.
Curcumin influences a number of physiological processes, including female reproduction (puberty, reproductive aging, ovarian folliculogenesis and oogenesis, and fecundity) through changes in the dynamics of release and reception of pituitary and ovarian hormones, growth factors, and cytokines.
In addition, it appears to be able to influence the response of ovarian cells to these substances as well as to external environmental factors.
Curcumin may also affect oxidative processes within the ovary and several intracellular signaling pathways related to ovarian cell proliferation and apoptosis.
These effects suggest its potential application for the stimulation of female reproductive processes in vivo and in vitro, as well as for the prevention, mitigation, and treatment of certain reproductive disorders, such as ovarian failure or polycystic ovary syndrome.
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Source: Alexander V Sirotkin. The lnfluence of Turmeric and Curcumin on Female Reproductive Processes. Pianta Med 2022: 88(72)’ 1020-1025. 00/.’ 70 7055/a-7542-8992.
