GFI Publishes Clinical Study on Dietary Supplement (Cresko) for Asthenic Children: Psychosocial and Emotional Benefits
The early years of life represent a critical phase in the overall development of children, profoundly influencing their future physical, social, cognitive, and emotional outcomes. Interventions adopted during this period, between 3 and 10 years old, offer significant benefits compared to lifestyle modifications and corrective interventions later in adolescence and adulthood.
In particular, nutrition plays a fundamental role: malnutrition in the first two years can have lasting consequences on Intelligence Quotient (IQ), school performance, and future employment. Micronutrient deficiencies like iron are directly associated with impaired cognitive development.
Globally, iron deficiency anemia affects a significant portion of children, not only in developing countries but also in industrialized ones. Studies highlight that royal jelly, for example, can benefit gastrointestinal health and cognitive performance, confirming the crucial role of micronutrients.
Integrating substances like glutamine could offer further advantages, such as neural protection and reduction of muscle damage. In summary, investing in the early stages of development through targeted interventions can significantly improve children’s future quality of life, positively influencing their physical health and their psychosocial and cognitive well-being.
The objective of our study was to determine whether the administration of a dietary supplement (Cresko) containing iron, glutamine, and royal jelly has positive effects on the psychosocial and emotional state of asthenic children.
Method of the Longitudinal Study
The study design is a single-arm longitudinal evaluation, conducted prospectively including patients from outpatient clinics of three family pediatricians.
Patients were treated with a dietary supplement (Cresko) containing iron, royal jelly, glutamine, and B vitamins, at a dose of 2 oral vials per day, for 30 days.
The effectiveness of the psychosocial and emotional symptoms of the child was assessed through the modified Patient Health Questionnaire 9 for pediatric patients (aPHQ9). Patients were followed for at least 30 days.
Study Results
Seventy-one children with a mean age of 7.2 ± 2.6 years were included in the study and completed follow-up at an average of 30 ± 7.2 days. The baseline mean aPHQ9 was 11.5 ± 4.9 points, which decreased to 3.8 ± 4.3 points at follow-up (p<0.001).
Through a linear regression model, the effect of sex, age, baseline weight, duration of treatment, and weight gain on the pre-post difference of aPHQ9 was evaluated. The findings revealed a significant positive correlation for age (p=0.004), days of treatment (p<0.001), and weight gain (p=0.002). No short-term adverse events were observed.
In conclusion, oral supplementation with iron, fresh royal jelly, and glutamine – contained in the vials of our dietary supplement Cresko – effectively improves children’s psychosocial state.
If you are interested in becoming a distributor of the dietary supplement Cresko in private label/out-licensing or want more information about our clinical study
Source: Anno VIII, N.2 – Giugno 2023, Pharmanutrition and Functional Foods.
